CHIN-LIN CHEN
Work experience
2023-now
University of Lausanne (UNIL)
Postdoctoral Project Leader
● Improved a behavior classifier's performance from 72% to 92% accuracy by combining computer version and deep learning tools.
● Automated a bioimaging system with the assembly of sensors/cameras and software design of a programmable interface for a novel drug-screening platform.
● Published a review of current research progress of cancer drug repurposing for neurodevelopmental disorder.
2017-2022
Swiss Federal Insitute of Technology (EPFL)
Doctoral Researcher
● Uncovered neural mechanisms for behavior control by prototyping a bioimaging system and computer vision engineering for object tracking and behavior classification.
● Expanded the capacity of an existing behavior classifier by integrating a newly trained deep-learning model of pose estimation.
● Multivariate analysis to extract features from a large-scale time-series dataset by machine learning and statistical analysis.
● Project management on data-driven decision-making, communication with data visualization and scientific writing, and cross-functional collaboration of 3 team members to lead 3 collaborations to success (JRC and Columbia University, USA; King’s college, UK).
2014-2017
National Tsing Hua University
National Yang Ming University
Electrophysiology specialist
● Patch-clamp to study single-cell electrophysiology to understand the neuronal and synaptic mechanisms in memory formation.
● Analyzed the electrical signal from neurons using spike detection and waveform analysis, and object tracing from morphological image datasets.
Education
2017-2022
Ph.D. in Neuroscience
Neuroengineering laboratory, Swiss Federal Insitute of Technology (EPFL)
● Bioimaging, Large-scale data analysis, Image analysis, Behavior analysis, Machine learning
2011-2013
Master in Neuroscience
Graduate Institute of Brain and Mind Sciences, National Taiwan University (NTU)
● Signal analysis, Electrophysiological recording, rodent experiment
2007-2011
Bachelor in Forestry
Forestry and resource conservation, National Taiwan University (NTU)
● Profit and cost modeling of the biofuel supply chain
Skills
Data science: Large-scale bioimage and time-series analysis, Statistics, Machine learning, Data visualization.
Programming tools: Python, Git, Linux command, SQL, Docker, LaTeX (Overleaf),
Python toolkits: NumPy, Pandas, Matplotlib, Pytorch, Scikit-learn
Soft skills: Problem-solving, Proactive Communication, Influencing without authority, Team spirit.
Certifications and Awards
PRINCE2 Project Management – PeopleCert, Switzerland
AgilePM Agile Project Management – APMG International, Switzerland
Innosuisse Business Concept - Travel Award - EPFL Innovation Park, Switzerland
Publications
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“Cancer drug repurposing in autism spectrum disorder.” Georgia Pedini, Chin-Lin Chen, Tilman Achsel, Claudia Bagni. Trends in pharmacological sciences, 44(12), p.963–977, 2023
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“Ascending neurons convey behavioral state to integrative sensory and action selection centers in the brain.” Chin-Lin Chen, Florian Aymanns, Ryo Minegishi, Victor D. V. Matsuda, Nicolas Talabot, Semih Günel, Barry J. Dickson, Pavan Ramdya. Nature Neuroscience, 26, p,682-695, 2023
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“Imaging neural activity in the ventral nerve cord of behaving adult Drosophila.” Chin-Lin Chen1, Laura Hermans1, Meera C Viswanathan, Denis Fortun, Florian Aymanns, Michael Unser, Anthony Cammarato, Michael H Dickinson, Pavan Ramdya. Nature Communications, 9, p.4390, 2018
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“Descending neuron population dynamics during odor-evoked and spontaneous limb-dependent behaviors.” Florian Aymanns, Chin-Lin Chen, Pavan Ramdya. eLife, 11:e81527, 2022
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“Microengineered devise enable long-term imaging of the ventral nerve cord in behaving adult Drosophila.” Laura Hermans, Murat Kaynak, Jonas Braun, Victor Lobato-Rios, Chin-Lin Chen, Semih Günel, Florian Aymanns, Mahmut Selman Sakar, Pavan Ramdya. Nature Communications, 13, p.5006, 2022
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“Extensive and diverse patterns of cell death sculpt neural networks in insects.” Sinziana Pop, Chin-Lin Chen, Connor J Sproston, Shu Kondo, Pavan Ramdya, Darren W Williams. eLife, 9, p.e59566, 2020
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“Serotonergic modulation of walking in Drosophila.” Clare E Howard, Chin-Lin Chen, Tanya Tabachnik, Rick Hormigo, Pavan Ramdya, Richard S Mann. Current Biology, 29(23), p.4218-4230, 2019
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“Causal evidence for the role of specific GABAergic interneuron types in entorhinal recruitment of dentate granule cells.” Cheng-Ta Lee, Min-Hua Kao, Wen-Hsien Hou, Yu-Ting Wei, Chin-Lin Chen, Cheng-Chang Lien. Scientific Reports, 6(1), p.1-13, 2016